Autoimmune Disease and Missing Puzzles: A Cure for… Misdiagnosis? Dr. Johann Lechner’s Dental Research on RANTES

by | Dec 4, 2023 | Chronic Disease, Dental | 0 comments

Do you have one of those autoimmune diseases of “many names” after years of struggling and searching for help with your chronic physical ailments? The rate of the Autoimmune Disorders has risen rapidly in the last 40 years, and has become one of the most common medical diagnoses with a multitude of physical signs and symptoms. Autoimmunity is a medical enigma and epidemic out of proportion despite advancement in medical science.

One in ten people develop an autoimmune disease (more women than men), and the diagnosis rate is rising. There are now about a hundred classified autoimmune diseases. Among the most well-known are lupus, rheumatoid arthritis, Hashimoto’s disease, Grave’s thyroiditis, psoriasis, type 1 diabetes, Crohn’s disease, ulcerative colitis, mixed connective tissue disease, chronic inflammatory demyelinating polyneuropathy, and more.

The list is growing, and we do not have a clear understanding of the science behind why our immune cells are attacking out own bodies. Infections, environmental toxins, and genetics are the leading candidates for triggering autoimmune response, but are there other factors that have been overlooked? Did we miss something unknown to us, and in naming the disease based on laboratory test results and physical symptoms, do we overlook the underlying problems? Can we connect the dots, and find the missing links? Let’s investigate under our noses, close to our brains, thyroid, and at the opening to the airway and the gut: the oral cavity, for dental-related problems.

Is it possible that autoimmune disease is a misdiagnosis based on our limitation of medical science? We know one of the hallmarks of this category is inflammation, with some sort of antibodies developed as inflammatory markers to our tissues and organelles, and at the DNA level. As an example, a diagnosis for lupus includes a battery of blood tests including antinuclear antibody (ANA) test, different imaging tests like Chest X-ray and echocardiogram, and tissue biopsy like skin or kidney.

Treatment is limited based on your signs and symptoms. It could be ibuprofen, an antimalarial parasite medication like hydroxychloroquine, steroids, immunosuppressant drugs, and new biologics like Rituxan (Rituximab) which can also be used for rheumatoid arthritis and non-Hodgkin’s Lymphoma. If you do not correct the true underlying problems, you became a part of the medical system as a permanently labeled lupus patient. Is there a solution to autoimmune disease?

Let me explain. We should not dwell on the diagnosis. Once the diagnosis is made by specialists, the primary focus is to treat the symptoms. Sometimes it is better off ignoring the diagnosis. Starting with a fresh point of view, I check 40 main meridian points based on acupuncture meridian assessment (AMA), and develop a treatment plan based on addressing the biggest problems first. Lab test results can be used compare how patients are responding to correcting the underlying problems.

My conclusion over the years on the main reasons patients are not getting well: neglected dental problems, parasite infections, and environmental toxins including heavy metals and mycotoxins. For example, see a case study of 46-year-old female with lupus, pericarditis, tachycardia, anemia, alopecia and arthralgia in my first book, Accidental Cure, and article, Lupus: Autoimmune Disease and Hidden Pathogens. Elevated ANA, ESR, CRP, and other inflammatory markers all came down as dental work was done on dental cavitation (jaw infection). Chelation therapy lowered her mercury level, and multiple rounds of parasite medications also helped her to recover from her lupus diagnosis and become asymptomatic, without using immunosuppressive therapy.

Some people have multiple autoimmune disease concurrently such as Hashimoto’s thyroiditis, rheumatoid arthritis, interstitial pneumonitis, psoriasis and ulcerative colitis. Unless we can correct the upstream underlying problems, we end up treating symptoms, and dealing with the complications of the disease process itself, and the side effects of treatments. See above on how our immune system will tilt based on missing links. In most cases, genetics play a minor role compared to dental problems, parasites, and environmental toxin exposures.

Physicians rely on dentists to correct dental problems, and dental issues are the most overlooked missing links. There is a medical-and-dental (MAD) disconnection. The International Academy of Oral Medicine and Toxicology (IAOMT) and International Academy of Biological Dentistry and Medicine (IABDM) have been working to end use of mercury dental amalgams, warning about root canals, and more recently, focusing on the dangers of jaw infection from previously extracted teeth, including wisdom teeth.

Dr. Johann Lechner, DDS of Germany is a leading researcher on dental infections, especially jaw infections with osteonecrosis, known as fatty degenerative osteonecrosis of the jaw (FDOJ). He finds immune dysregulation, with overexpression of an inflammatory cytokine called RANTES (short for regulated upon activation, normal T-cell expressed and secreted), see figure below. High RANTES has been associated with osteonecrosis of the jawbone (cavitation), and with breast cancer, chronic fatigue syndrome, neuropathy, and rheumatic diseases, among many medically unexplained conditions.

One of the major cruxes of the problem is that routine dental X-rays will not reveal jaw infections until there is significant bone damage. Even CT cone beam dental X-ray (CBCT), the gold standard, may miss osteonecrosis of jawbone unless there is 10-15% bone destruction or more.  The early warning signs for dental and jaw problems can be picked up based on energetic evaluation using acupuncture meridian assessment (AMA).

If we understand energy medicine, a cure from autoimmune disease is possible and this is not an accidental cure. My book, AcciDental Blow Up in Medicine: Battle Plan for Your Life, will guide you in treating misunderstood autoimmune diseases. IAOMT and IABDM are the leading biological dental organizations. A strong physician-dentist team can connect the missing links of medical and dental problem, and go beyond (mis-)diagnosis to treatment. Success or failure in your recovery is often based on dental work done correctly, a missing piece of the puzzle for autoimmune diseases.

Dr. Simon Yu, MD is a Board Certified Internist. He practices Internal Medicine with an emphasis on Integrative Medicine to use the best each has to offer. For more articles and information about integrative medicine, patient success stories, and Dr. Yu’s latest book, AcciDental Blow Up in Medicine: Battle Plan for Your Life, visit his website at or call Prevention and Healing, Inc., 314-432-7802. You can also attend a free monthly presentation and discussion on Integrative Medicine at his office on the second Tuesday each month at 6:30 pm. Call to verify the date. Seating is limited, arrive early. Dr. Yu teaches Acupuncture Meridian Assessment (AMA) seminars to physicians, dentists, and prescribing health professionals in April and June of each year, with an advanced training for AMA graduates in August.